Her study found the glymphatic clearance was mediated by a hormone called norepinephrine and happened almost exclusively during the NREM sleep phase. But it only worked when sleep was natural. Anesthesia and sleeping pills shut this process down nearly completely.
I love it for bedtime and it helps my autoimmune shit. Glad it’s not brain bad.
Aside from possibly becoming a dependency, I’d imagine it doesn’t interfere with sleep quality. It’s what builds up in your body to make you sleepy/fall asleep.
Too much might keep you groggy in the morning though.