A new discovery reveals that astrocytes, star-shaped cells in the brain, play a key role in regulating fat metabolism and obesity. These cells act on a cluster of neurons, known as the GABRA5 cluster, effectively acting as a “switch” for weight regulation.
The MAO-B enzyme in these astrocytes was identified as a target for obesity treatment, influencing GABA secretion and thus weight regulation.
KDS2010, a selective and reversible MAO-B inhibitor, successfully led to weight loss in obese mice without impacting their food intake, even while consuming a high-fat diet, and is now in Phase 1 clinical trials.
I mean technically, if it’s a tube, the mouth is part of the basic physics brain process. As in, if you don’t eat it, it won’t be added to the calories. The decision to eat is a brain process, too.
We’ve got drugs that play with that decision.
It’s also easy easier to discriminate against far people if you can define it as a moral failure of just not putting food in your gob.
Unlike close people. Those are always bastards invading personal spaces.
Unless you don’t eat at all, the decision to eat is secondary to the decision to absorb energy from it.
For example, I’ve been eating a “healthy diet” with about the same amount of exercise, for the last 3 years: first it kept my weight steady, then I lost 70 pounds in 3 months, then gained 10.
The only difference: stress levels.
People have been congratulating me for
losing weightgetting stressed out of my mind to the point of almost going crazy and killing myself. Thanks, but I was better before.I hope you are doing better now.