3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%.
A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and routine dental visits help in prevention, there’s always room for improvement.
Researchers from Ben-Gurion University of the Negev, in collaboration with teams from Sichuan University and the National University of Singapore, have identified that 3,3′-Diindolylmethane (DIM) – a naturally occurring molecule also referred to as bisindole – can reduce biofilms responsible for plaque and cavities by a remarkable 90%.
The molecule is also found to have anti-carcinogenic properties.
Their findings were recently published in the journal Antibiotics.
Incredible. Given how expensive dental treatment is in a lot of places, this could be revolutionary for people who can’t afford regular checkups and/or treatment plans. It’s not going to be a replacement but it can certainly mitigate a lot of damage.
I mean if the research a few months ago in japan that detailed the ability to introduce a drug to allow teeth growth beyond the second pair has good results, things are getting places.
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So… hold onto your teeth instead.
From my understanding , it wasn’t past the second pair, it was to reactivate deactivated teeth.
As in, they artificially induced a way to stop a tooth forming (which can occur naturally in humans), and then reactivated it. Useful for folks who suffer from agenesis in the first place.
Dentists hate this one complex molecule
Fuck’m. I’m pretty sure most of my “small cavities” over the years were nothing, especially in the 80s. Medieval butchery.
As grandpa said “don’t go to the dentist, they want you to keep your teeth as long as possible so they can keep billing you”
Well let’s hope the mass adoption of this ingredient in everyone’s toothpaste doesn’t make the gray water kill all the birds or frogs or something. Ecosystems are weird. Diclofenac fucks all the vultures and I found out recently.
The rub on cremes especially. How come everything we touch turns to hellscape.
Does it occur naturally in anything or would it be a toothpaste ingredient?
For anyone wondering, all those are the same species.
Brassica oleracea.
That must be why my teeth have never been a problem. Fuckin love broccoli
Yay cabbage!
DIM was found to be a mild cannabinoid agonist
Interesting…
agonist
Weed does everything!
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#JustCalgaryThings
#JustCavityThings
#JustColgateThings
Alcohol-based mouth sanitizer will kill like 99.9% of bacteria in your mouth, the issue is that you won’t keep it in your mouth 24 hours a day.
Is this new chemical supposed to be added to food, or maybe to sugar?
The point isn’t that it kills bacteria, it’s that it breaks down the biofilm.
The biofilm is basically habitat - it’s a structure they can cling to and establish a foothold.
Mouths are never going to be a sterile environment even a minute after nuking with alcohol; populations will re-establish in no time.
The point here is to deny them a place to stay.
That makes sense
You really don’t want to kill all the bacteria in your mouth.
Sounds like this molecule is already found in broccoli, kale, Brussels sprouts, and cabbage.
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