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Cake day: March 5th, 2024

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  • Relevant Section on the genetics:

    For the study, the researchers took blood from five of the cats, which had been adopted, and conducted a DNA test on four of the felines, which turned up no genetic mutations associated with white fur.

    They then performed a whole genome sequencing for two of the cats, and this step turned up a deletion in what’s called the KIT gene, which can encode whether white will turn up in a feline’s coat (scientists have also connected variations in the KIT gene to piebald patterns in various animals like horses and mice.)

    “In summary, comparative data from other species and genotype segregation analysis support the newly discovered KIT region deletion as potentially being a cause of salmiak coat color in cats,” the researchers conclude.



  • Relevant section of the article where it lays out what has been changing and what still needs to change:

    … graft has been all but exterminated in some of the worst affected areas - for instance, government services such as issuing passports, permits and licences.

    He also tells the BBC that significant progress had been made in reforming education and police.

    Problem areas

    Mr Kalmykov admits, however, that the government has been less successful in eradicating corruption in using natural resources (e.g. in mining and forestry), regulating monopolies and in large infrastructure projects.

    “Progress has been slowest where big interests and big players meet,” he says.

    According to him, “in the next five-ten years the government should focus on cleansing the judiciary, which will make the general system of public administration healthier”.



  • That’s a good point about disease and I think it could be a potential cause of the low genetic prevalence.

    I don’t know about your roaming free option. I think if that were true, there would still be wild packs today or there would have been roving dog packs mentioned in historical text (possible but I don’t recall any mention of them). Alternatively, they would have inter-breed with European varieties and had a more significant impact on genetics, but that’s not seen.

    While I agree that Europeans liked to remove/exterminate “uncivilized” things, that mostly applies to people. I suspect if the American dogs were significantly useful they would have made use of them.

    This conversation allowed me to recall that the plains tribes utilized dogs as pack animals. Then once horses made their way onto the scene those tribes switched from dogs to horses for that role. I’m not sure what other “jobs” American dogs performed but I suspect if they were significantly utilized as pack animals they were probably breed for such and with that niche gone they may not have performed well in other “dog” tasks, compared to European varieties.

    To conclude, for American dogs to be such a small percent of the current dog genome, I think, the European varieties had to significantly outlive their American counterparts. Whether because they were replaced by better performing European varieties/horses, because they died from European diseases, or a combination of those options.