I call it “comic book guy” syndrome. The desperate need to feel superior.

“Search before asking!” - Stack Overflow

You’ve been Grokked!

My company pushes us to use copilot and I end up going back to chatgpt (I use them mainly as glorified search engines, error code debuggers and coding assistants). Copilot constantly has availability issues. Sort of tough to use a site that isn’t available.

Well if you want to be more than a worm you really need the brain. There is a reason most of your senses are clustered in your head.

Neurotransmitters in the gut cannot reach the brain due to the blood brain barrier (or very limited at best). Reuptake proteins and breakdown enzymes also prevent outside neurotransmitters from interfering. Your gut already produces large amounts of serotonin and it was first identified in the gut. 90% of the serotonin in the body is made in the lining of the stomach where it modulates smooth muscle contractions. About 50% of the dopamine is produced in the gut also.

However, microbes could affect gut behavior and that could effect mood simply by feeling poorly or well. There is also the matter of inflammatory responses and signaling (i.e. cytokines) that could affect one’s general sense of health. The small intestine is packed with immune cells that will also react to changes in the gut biome.

Finally there is the vagus nerve, a highway running from the gut, lungs and heart straight to the hindbrain, bypassing the spine. More here. We are still learning about how much this ancient nerve controls and influences. I’ve even wondered if it is related to dementia and Parkinson’s because of its physical proximity to locations such as the substantia nigra (Parkinson’s) and areas that show the first signs of dementia, possibly due to influences traveling up the nerve similar to the way rabies viruses travel. People who have had their vagus nerve cut, in an effort to stop severe stomach ulceration, showed a significant drop in Parkinson’s. More here, and here.

I realized this when I first visited Mexico, what you see here is not necessarily representative of that nation. The people who come here are the hungry ones looking to make money or just get out of Mexico. When I went to Mexico City I suddenly saw lots of BMWs, Mercedes, nice homes (and a lot of rough areas), etc. The people who come here come here because they are poor and ambitious/desperate, the well to do ones stay there.

A similar thing with Indian immigrants but we get the ones with higher education, the money to leave and live here, fluent in English, curious and ambitious, etc. The poor and uneducated aren’t coming over.

I’m going to say you shouldn’t be shocked that people like this aren’t the most insightful or analytical minds.

Pretty ballsy taking down trump’s twitter account.

Yup, it would take mass unemployment and the impoverishment of the average person to trigger anything like happened in 1920s Germany.

lol what? The US is full of guns and they just seem to get used for road rage, robberies and the occasional mass murder.

Internal collapse and/or a foreign coalition. If the US goes after Greenland I’d hope the rest of NATO stuck to their treaty obligations and fought back.

The question is “Does 15-PGDH do something beneficial and would suppressing it have serious side effects?”

I found this:

15-HPGD has an unappreciated role in the maintenance of pregnancy. In mice, 15-HPDG has been shown to have essential roles in prevention of early termination of pregnancy and maternal morbidity. In 15-HPGD knockout mice, early pregnancy termination was detected.

So any 15-HPGD treatment would have to be done with careful consideration of woman of reproductive age.

I wonder if you’d have to stay off of those joints for months to allow the regrowth to occur properly.

The only real solution isn’t reactivating roombas but cutting dependence on US goods and markets. The US market is highly desirable from a purely population angle but isn’t essential today. Moving to an alternative to the dollar, expanding production of essential goods to other nations, etc.

If you really want to spite the US use retaliatory IP lifting. “Ok, US IP protections are now invalid.”

Fortunately a good number of comments point out that it is AI crap. For some reason the majority of these videos come from Pakistan and the middle east.

He’ll be in his Hawaii bunker.

FB is also a sea of AI videos that are being passed off as real.

Same, it is mainly a messaging platform for me for people who I otherwise can’t reach.

I have all of those things and get regular cleanings. No whitening toothpaste or treatments.