• 0 Posts
  • 31 Comments
Joined 1 year ago
cake
Cake day: June 11th, 2023

help-circle

  • Tvkan@feddit.detoMicroblog Memes@lemmy.worldLimited time offer
    link
    fedilink
    English
    arrow-up
    26
    ·
    edit-2
    10 months ago

    We’re talking about glioblastoma here, there’s not much “continous” treatment to be had and temozolomide’s and bevacizumab’s patents have run out (edit: also bevacizumab doesn’t prolong overall survival at all and temozolomide is ineffective in MGMT-positive patients, i.e. about half).

    That said, I’m not sure why the other commenter is so dismissive of your idea. There’s plenty of drugs that have been kept in the cupboard (e.g. desloratadine) or not seeking approval for certain illnesses so a “new”, more expensive drug could be sold (e.g. no rituximab trials for multiple sclerosis so Roche could sell Ocrelizumab, no Bevacizumab trials for macular degeneration so they could sell Ranibizumab) – and certainly many more that we never heard about.



  • Tvkan@feddit.detoMicroblog Memes@lemmy.worldSlightly different approaches
    link
    fedilink
    English
    arrow-up
    8
    arrow-down
    5
    ·
    10 months ago

    Europe very sound protection for the disabled. Putside of historical buildings built before disability care you won’t find better access anywhere.

    But that’s the point: Most buildings were built before disability care, and haven’t been upgraded.* Think about your favorite restaurant, bar, kebab place, corner shop etc. – I don’t think any of mine are wheelchair accessible. Also good luck taking a train in Germany, where many platforms aren’t wheelchair accessible and they might or might not have a lift to get you into the train.

    The Americans with Disabilites Act (ADA) is miles ahead of any legal framework that I’m aware of in Europe. The US is a broken country in many ways, but that doesn’t mean that literally anything and everything has to be worse than in glorious Europe.

    *The former is true for the US too, but the ADA still required many of them to make reasonable accomodations.

















  • Tvkan@feddit.detointernet funeral@lemmy.worldBut I like it this way
    link
    fedilink
    English
    arrow-up
    57
    arrow-down
    1
    ·
    edit-2
    1 year ago

    I know you’re making a joke, but this really is a (ihmo very interesting) mess:

    In this case this is just multiple single points of failure though, at least for the larger ones.

    If you lose one of the big red ones in the middle (common carotid arteries) you’ll have a major stroke killing essentially three quarters of one of your hemispheres.

    There’s another pair in the spine (vertebral arteries, not visible) which supply the posterior and lower parts of your brain, but they’re also not redundant. Also sometimes, one’s doing basically all of the heavy lifting, and sometimes the other one doesn’t exist at all.

    Also this is a simplification and many many variations exist.