Fun fact: the opposite of estrogenize is in fact to androgenize. No relation to androgynize with a Y, they’re just one letter apart and for many speakers 100% homophonic, but they’re very different in meaning, if we’re talking about men’s sex hormone intake.
Makes me think of The Boondocks: “[It’s] n###a technology — technology for n###as. Only don’t start trippin’ and shit, callin’ me a racist, 'cause I don’t mean n###a in a disrespectful way — I mean it as a general term for ignorant motherfucker.”